BDBM50041679 CHEMBL3358892
SMILES C[C@H](N1C[C@@H](C)[C@@H](CN(C)C(=O)Nc2ccc(cc2)C(F)(F)F)Oc2c(NS(=O)(=O)c3ccc(F)cc3)cccc2C1=O)C(O)=O
InChI Key InChIKey=XAEPMFMCFFIZDH-FUMQJTLXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50041679
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) using TAMRA-labeled Noxa peptide preincubated for 30 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataKd: 6.00E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) by 19F NMR spectroscopyMore data for this Ligand-Target Pair