BDBM50041679 CHEMBL3358892

SMILES C[C@H](N1C[C@@H](C)[C@@H](CN(C)C(=O)Nc2ccc(cc2)C(F)(F)F)Oc2c(NS(=O)(=O)c3ccc(F)cc3)cccc2C1=O)C(O)=O

InChI Key InChIKey=XAEPMFMCFFIZDH-FUMQJTLXSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041679   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50041679(CHEMBL3358892)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50041679(CHEMBL3358892)
Affinity DataIC50:  4.50E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) using TAMRA-labeled Noxa peptide preincubated for 30 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50041679(CHEMBL3358892)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to human MCL1 (173 to 329 aa) by 19F NMR spectroscopyMore data for this Ligand-Target Pair