BDBM50042236 4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL115771

SMILES OC(=O)c1ccccc1-c1ccc(CN2C(Cc3ccccc3)=NC3(CCCC3)C2=O)cc1

InChI Key InChIKey=AKPSJDJJPBXDJU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042236   

TargetType-1 angiotensin II receptor B(RAT)
Sanofi Recherche

Curated by ChEMBL
LigandPNGBDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute For Translational Medicine And Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50:  8.65E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute For Translational Medicine And Phamacology Itmp

Curated by ChEMBL
LigandPNGBDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataEC50:  6.58E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed