BDBM50042251 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL116170
SMILES CCCCC1=NC2(CCCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O
InChI Key InChIKey=MFRBWXHTGUQKIS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50042251
Affinity DataIC50: 7.20nMAssay Description:Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Affinity DataIC50: 155nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair