BDBM50042930 CHEMBL3354569::US9512126, 6

SMILES Cc1cc(ccc1C(=O)NC1CC1)-c1cnc2c(NCCC(F)(F)F)cc(nn12)C(F)(F)c1cccc(F)c1

InChI Key InChIKey=LQFNIVXTFUWHQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042930   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50042930(CHEMBL3354569 | US9512126, 6)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Mps1 (unknown origin) activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM50042930(CHEMBL3354569 | US9512126, 6)
Affinity DataIC50:  0.700nMpH: 7.7 T: 2°CAssay Description:The human kinase Mps-1 phosphorylates a biotinylated substrate peptide. Detection of the phosphorylated product is achieved by time-resolved fluoresc...More data for this Ligand-Target Pair
In DepthDetails US Patent