BDBM50042931 CHEMBL3354995::US9512126, 16

SMILES COc1ccc(cc1)C(F)(F)c1cc(NCCC(F)(F)F)c2ncc(-c3ccc(C(=O)NC4CC4)c(C)c3)n2n1

InChI Key InChIKey=WFKFFDJSURRIRZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042931   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50042931(CHEMBL3354995 | US9512126, 16)Copy SMILESCopy InChI

Affinity DataIC50:  0.600nMAssay Description:Inhibition of Mps1 (unknown origin) activity by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity protein kinase TTK/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property

US Patent

LigandBDBM50042931(CHEMBL3354995 | US9512126, 16)Copy SMILESCopy InChI

Affinity DataIC50:  0.600nMpH: 7.7 T: 2°CAssay Description:The human kinase Mps-1 phosphorylates a biotinylated substrate peptide. Detection of the phosphorylated product is achieved by time-resolved fluoresc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails US Patent
Copy BDB DOI