BDBM50042973 1-(4-Chloro-phenyl)-3-(3,4-dihydroxy-phenyl)-propenone::1-(4-chlorophenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one::4'-chloro-3,4-dihydroxychalcone::CHEMBL127593

SMILES Oc1ccc(\C=C\C(=O)c2ccc(Cl)cc2)cc1O

InChI Key InChIKey=NPDXBNMNUDCDHM-LREOWRDNSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042973   

TargetStromal cell-derived factor 1(Homo sapiens (Human))
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50042973(1-(4-Chloro-phenyl)-3-(3,4-dihydroxy-phenyl)-prope...)
Affinity DataKi:  350nMAssay Description:Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042973(1-(4-Chloro-phenyl)-3-(3,4-dihydroxy-phenyl)-prope...)
Affinity DataIC50:  8.5nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed