BDBM50043352 10-(3,4-Dihydroxy-benzylidene)-1,8-dihydroxy-10H-anthracen-9-one::10-(3,4-dihydroxybenzylidene)-1,8-dihydroxyanthracen-9(10H)-one::CHEMBL130560

SMILES [#8]-c1ccc(\[#6]=[#6]-2\c3cccc(-[#8])c3-[#6](=O)-c3c(-[#8])cccc-23)cc1-[#8]

InChI Key InChIKey=HAOIGARVPBUDHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043352   

Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043352(10-(3,4-Dihydroxy-benzylidene)-1,8-dihydroxy-10H-a...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043352(10-(3,4-Dihydroxy-benzylidene)-1,8-dihydroxy-10H-a...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed