BDBM50043462 CHEMBL335066::{[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenyl]-propyl-amino}-phenyl-acetic acid

SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C

InChI Key InChIKey=AXZWSJDQELCLKP-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043462   

TargetType-2 angiotensin II receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043462(CHEMBL335066 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...)
Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C
Show InChI InChI=1S/C29H34N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h8-14,16-17,27H,6-7,15,18H2,1-5H3,(H,34,35)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043462(CHEMBL335066 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...)
Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C
Show InChI InChI=1S/C29H34N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h8-14,16-17,27H,6-7,15,18H2,1-5H3,(H,34,35)
Affinity DataIC50: 12nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair