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BDBM50045459 CHEMBL3309811

SMILES: Oc1ccc(\C=C\C(=O)N2CCN(CC2)c2ccccc2F)cc1O

InChI Key: InChIKey=VMRXWLNCTNRGSN-SOFGYWHQSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045459   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50045459
PNG
(CHEMBL3309811)
Show SMILES Oc1ccc(\C=C\C(=O)N2CCN(CC2)c2ccccc2F)cc1O
Show InChI InChI=1S/C19H19FN2O3/c20-15-3-1-2-4-16(15)21-9-11-22(12-10-21)19(25)8-6-14-5-7-17(23)18(24)13-14/h1-8,13,23-24H,9-12H2/b8-6+
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.78E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric method


Bioorg Med Chem 22: 4285-92 (2014)


Article DOI: 10.1016/j.bmc.2014.05.029
BindingDB Entry DOI: 10.7270/Q21Z462G
More data for this
Ligand-Target Pair