BDBM50045736 3-{1-[2-(3-Fluoro-phenyl)-ethyl]-3,4-dimethyl-piperidin-4-yl}-phenol::CHEMBL94409

SMILES C[C@H]1CN(CCc2cccc(F)c2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=HCCVFSPHCNXGBG-HRAATJIYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045736   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045736(3-{1-[2-(3-Fluoro-phenyl)-ethyl]-3,4-dimethyl-pipe...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]-NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045736(3-{1-[2-(3-Fluoro-phenyl)-ethyl]-3,4-dimethyl-pipe...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at 10 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045736(3-{1-[2-(3-Fluoro-phenyl)-ethyl]-3,4-dimethyl-pipe...)
Affinity DataKi:  93nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at 100 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed