BDBM50047260 4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile::4-[(4-cyanophenyl)(1H-imidazol-1-yl)methyl]benzonitrile::4-[4-cyanophenyl(1H-1-imidazolyl)methyl]benzonitrile::CGS-18320B::CHEMBL29482

SMILES N#Cc1ccc(cc1)C(c1ccc(cc1)C#N)n1ccnc1

InChI Key InChIKey=NRXVWQIGPASRKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50047260   

TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047260(4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile |...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047260(4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile |...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047260(4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile |...)
Affinity DataIC50:  4nMAssay Description:Inhibition of aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate after 30 mins by fluorescence-based colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed