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BDBM50047886 4-Amino-quinoline-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::CHEMBL160147

SMILES: CN1C2CCC1CC(C2)NC(=O)c1cnc2ccccc2c1N

InChI Key: InChIKey=SQLJERVACOKVCT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50047886
PNG
(4-Amino-quinoline-3-carboxylic acid (8-methyl-8-az...)
Show SMILES CN1C2CCC1CC(C2)NC(=O)c1cnc2ccccc2c1N
Show InChI InChI=1S/C18H22N4O/c1-22-12-6-7-13(22)9-11(8-12)21-18(23)15-10-20-16-5-3-2-4-14(16)17(15)19/h2-5,10-13H,6-9H2,1H3,(H2,19,20)(H,21,23)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.


J Med Chem 36: 617-26 (1993)


Article DOI: 10.1021/jm00057a011
BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair