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BDBM50047893 4-Hydroxy-quinoline-3-carboxylic acid (1-aza-bicyclo[3.3.1]non-4-yl)-amide::CHEMBL346272

SMILES: Oc1c(cnc2ccccc12)C(=O)NC1CCN2CCCC1C2

InChI Key: InChIKey=ZWTGKOYRFIUHAO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047893   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50047893
PNG
(4-Hydroxy-quinoline-3-carboxylic acid (1-aza-bicyc...)
Show SMILES Oc1c(cnc2ccccc12)C(=O)NC1CCN2CCCC1C2
Show InChI InChI=1S/C18H21N3O2/c22-17-13-5-1-2-6-16(13)19-10-14(17)18(23)20-15-7-9-21-8-3-4-12(15)11-21/h1-2,5-6,10,12,15H,3-4,7-9,11H2,(H,19,22)(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
18n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.


J Med Chem 36: 617-26 (1993)


Article DOI: 10.1021/jm00057a011
BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair