BDBM50048233 1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmethyl)-piperazine::CHEMBL28321

SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1

InChI Key InChIKey=UPXJKNQVKALXKP-UHFFFAOYSA-N

Data  6 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50048233   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá di Bari

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Cercopithecus aethiops)
Neurogen Corporation

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-YM 09151 from african green monkey Dopamine receptor D2More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá di Bari

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-YM 09151 from human Dopamine receptor D4More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá di Bari

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá di Bari

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-YM-09151-2 from human Dopamine receptor D4.2 expressed in baculovirus Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Chlorocebus aethiops)
Neurogen Corporation

Curated by ChEMBL
LigandPNGBDBM50048233(1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmet...)
Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-11-12-25(18-19)20-7-3-2-4-8-20/h2-12,18H,13-17H2,1H3
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-YM 09151 from african moonkey Dopamine receptor D3More data for this Ligand-Target Pair