BDBM50048995 CHEMBL82325::N-Hydroxy-N-methyl-2-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-propionamide

SMILES CC(C(=O)N(C)O)c1ccc2OCc3ccccc3C(=O)c2c1

InChI Key InChIKey=GXPVTRYNVKFRPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048995   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048995(CHEMBL82325 | N-Hydroxy-N-methyl-2-(11-oxo-6,11-di...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed