BDBM50049164 (S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid::2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acidr;1.75H2O::CHEMBL169540::CHEMBL355543
SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)cc2c(=O)[nH]1
InChI Key InChIKey=CTVPMDSEKDRELN-ZEQRLZLVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50049164
Affinity DataKi: 1.10nMAssay Description:Inhibition of thymidylate synthase, partially purified from L1210 mouse leukemia cells overexpressing TSMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair