BDBM50049441 CHEMBL3356470

SMILES C[C@H]1N2C(COc3cc(C)c(NC4CNC4)cc23)=NNC1=O

InChI Key InChIKey=YWULJUISHNTGOC-SECBINFHSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049441   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Affinity DataIC50:  520nMAssay Description:Inhibition of human recombinant PKCbeta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
TargetProtein kinase C gamma type(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant PKCgamma expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50049441(CHEMBL3356470)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant PKCdelta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed