BDBM50049481 (R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-3-amino-3-methylbutanamide::3-Amino-3-methyl-N-{(R)-2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::3-Amino-3-methyl-N-{2-oxo-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::Arg-Pro-Lys-Pro-Phe-Trp-Leu::CHEMBL308716::L-692429

SMILES CC(C)(N)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O

InChI Key InChIKey=SBJLJOFPWOYATP-XMMPIXPASA-N

Data  1 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50049481   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataKi:  63nMAssay Description:Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataIC50:  60nMAssay Description:Inhibition of the compound against rat growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone-releasing hormone receptor(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataEC50:  60nMAssay Description:Ability to release growth hormone in a rat pituitary cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of the compound against human angiotensin II receptor, type 1 (AG2-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of the compound against human growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataEC50:  60nMAssay Description:In vitro growth hormone release was determined in rat pituitary cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Sus scrofa)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)
Affinity DataIC50:  63nMAssay Description:Inhibition of the compound against pig growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed