BDBM50049602 6-Phenylsulfanylmethyl-pteridine-2,4-diamine::CHEMBL279243

SMILES Nc1nc(N)c2nc(CSc3ccccc3)cnc2n1

InChI Key InChIKey=ZJOATKLQTCGUSP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049602   

TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  770nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Saccharomyces cerevisiae)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  770nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50049602(6-Phenylsulfanylmethyl-pteridine-2,4-diamine | CHE...)
Affinity DataIC50:  2.46E+5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed