BDBM50049635 5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-benzo[1,3]dioxole::CHEMBL416126

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCOc2c1

InChI Key InChIKey=GARKKXFHXDZJSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049635   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049635(5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049635(5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50:  12.0nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049635(5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed