BDBM50050394 6-[(3-Methoxy-5-trifluoromethyl-phenylamino)-methyl]-pteridine-2,4-diamine::CHEMBL23466

SMILES COc1cc(NCc2cnc3nc(N)nc(N)c3n2)cc(c1)C(F)(F)F

InChI Key InChIKey=YYDZTNXQOFTJJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050394   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050394(6-[(3-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  890nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050394(6-[(3-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050394(6-[(3-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  680nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed