BDBM50050397 6-(4-Chloro-phenylsulfanylmethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL22677::xv6-(4-Chloro-phenylsulfanylmethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine
SMILES Cc1c(CSc2ccc(Cl)cc2)cnc2nc(N)nc(N)c12
InChI Key InChIKey=UXHWDAJRTNZWPO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50050397
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Lindsley F. Kimball Research Institute
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair