BDBM50050398 6-[(2-Methoxy-5-trifluoromethyl-phenylamino)-methyl]-pteridine-2,4-diamine::CHEMBL23495

SMILES COc1ccc(cc1NCc1cnc2nc(N)nc(N)c2n1)C(F)(F)F

InChI Key InChIKey=BDWNMSMMYMMCBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050398   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050398(6-[(2-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050398(6-[(2-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050398(6-[(2-Methoxy-5-trifluoromethyl-phenylamino)-methy...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed