BDBM50050416 6-(3,4-Dimethoxy-phenylsulfanylmethyl)-pteridine-2,4-diamine::CHEMBL23286

SMILES COc1ccc(SCc2cnc3nc(N)nc(N)c3n2)cc1OC

InChI Key InChIKey=KVVYXYFMGZBRSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050416   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050416(6-(3,4-Dimethoxy-phenylsulfanylmethyl)-pteridine-2...)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050416(6-(3,4-Dimethoxy-phenylsulfanylmethyl)-pteridine-2...)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050416(6-(3,4-Dimethoxy-phenylsulfanylmethyl)-pteridine-2...)
Affinity DataIC50:  5.82E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed