BDBM50050429 6-[(5-Methoxy-2-methyl-phenylamino)-methyl]-pteridine-2,4-diamine::CHEMBL23560

SMILES COc1ccc(C)c(NCc2cnc3nc(N)nc(N)c3n2)c1

InChI Key InChIKey=QDLWXNKWIXCXRD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050429   

TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050429(6-[(5-Methoxy-2-methyl-phenylamino)-methyl]-pterid...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050429(6-[(5-Methoxy-2-methyl-phenylamino)-methyl]-pterid...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050429(6-[(5-Methoxy-2-methyl-phenylamino)-methyl]-pterid...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed