BDBM50050800 3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL305980

SMILES COc1nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)nc2OCCc12

InChI Key InChIKey=OQVTWUJKWGKZHT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050800   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  57nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed