BDBM50051340 2'-Hydroxyflavanone::2'-hydroxy-flavanone::2-(2-Hydroxy-phenyl)-chroman-4-one::2-(2-hydroxyphenyl)-2,3-dihydrochromen-4-one::CHEMBL75897
SMILES Oc1ccccc1C1CC(=O)c2ccccc2O1
InChI Key InChIKey=KZKWCKFDCPVDFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50051340
Affinity DataKi: 2.63E+3nMAssay Description:Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.64E+3nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain membranes by [3H]-PIA displacement.More data for this Ligand-Target Pair
Affinity DataKi: 6.03E+3nMAssay Description:Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6.07E+3nMAssay Description:Binding affinity against human adenosine A3 receptor in HEK293 cells using [125I]-AB-MECA 21680 radioligand.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 1.78E+4nMAssay Description:Ability to displace [3H]-CGS- 21680 binding from adenosine A2A receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) incubated for 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 (D3) using oracin as substrate measured after 30 mins in presence of NADPH ...More data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Inhibition of AchE in Rattus norvegicus (rat) cortex homogenates by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as reduction in DHT-induced transcriptional activation after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as reduction in DHT-induced cell growth treated for every 2 days for 4 days by hemocytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK-293 cells incubated for 10 minsMore data for this Ligand-Target Pair