BDBM50051349 4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one::CHEMBL45176::US11396516, Example visnagin

SMILES COc1c2ccoc2cc2oc(C)cc(=O)c12

InChI Key InChIKey=NZVQLVGOZRELTG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051349   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051349(4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | CHEM...)
Affinity DataKi:  4.27E+4nMAssay Description:Ability to displace [3H]-CGS- 21680 binding from adenosine A2A receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051349(4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | CHEM...)
Affinity DataKi:  6.00E+4nMAssay Description:Binding affinity against human adenosine A3 receptor in HEK293 cells using [125I]-AB-MECA 21680 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051349(4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | CHEM...)
Affinity DataKi:  6.03E+4nMAssay Description:Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCYP1A(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50051349(4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one | CHEM...)
Affinity DataIC50:  240nMAssay Description:The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maxi...More data for this Ligand-Target Pair
In DepthDetails US Patent