BDBM50051750 1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one::CHEMBL82807::WF-60

SMILES CCC(=O)C1C2CCC(CC1c1ccc(cc1)C(C)=C)N2C

InChI Key InChIKey=VVOZLVLHXLAANQ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051750   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50051750(1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50051750(1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50051750(1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  105nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransporter(Rattus norvegicus)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50051750(1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-nisoxatine from Norepinephrine transporter of rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM50051750(1-[3-(4-Isopropenyl-phenyl)-8-methyl-8-aza-bicyclo...)
Affinity DataIC50:  7.20nMAssay Description:Displacement of [125I]-RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed