BDBM50051827 CHEMBL283697::[4-((R)-2-Amino-3-mercapto-propyl)-piperazin-1-yl]-(2,3-dimethyl-phenyl)-methanone

SMILES Cc1cccc(C(=O)N2CCN(C[C@@H](N)CS)CC2)c1C

InChI Key InChIKey=VWWKWHDMKOYXDR-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051827   

LigandPNGBDBM50051827(CHEMBL283697 | [4-((R)-2-Amino-3-mercapto-propyl)-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051827(CHEMBL283697 | [4-((R)-2-Amino-3-mercapto-propyl)-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [3H]-FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed