BDBM50051886 CHEMBL289465::[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]dioxan-5-yl]-methanol

SMILES CC1(CO)COC(OC1)c1nc(c([nH]1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=WTRKWLHEIVJAHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051886   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886(CHEMBL289465 | [2-(4,5-Diphenyl-1H-imidazol-2-yl)-...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886(CHEMBL289465 | [2-(4,5-Diphenyl-1H-imidazol-2-yl)-...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886(CHEMBL289465 | [2-(4,5-Diphenyl-1H-imidazol-2-yl)-...)
Affinity DataIC50:  4.45E+3nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886(CHEMBL289465 | [2-(4,5-Diphenyl-1H-imidazol-2-yl)-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed