BDBM500520 7-[[5-[(3S)-3- hydroxy-1- piperidyl]-2- pyridyl]amino]-4-(1- methylpyrrolo [2,3-b]pyridin- 4-yl)-2,3- dihydropyrrolo [3,4-c]pyridin-1- one::US11021481, Compound I-179::US11078201, Compound I-179::US11548890, Compound I-179
SMILES Cn1ccc2c(ccnc12)-c1ncc(Nc2ccc(cn2)N2CCC[C@H](O)C2)c2C(=O)NCc12
InChI Key InChIKey=TXLWEGUVKCWRKE-INIZCTEOSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 500520
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Nimbus Saturn
US Patent
Nimbus Saturn
US Patent
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair