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BDBM50052621 5,6-Dichloro-1H-quinoline-2,3,4-trione 3-oxime::CHEMBL40708

SMILES: Oc1c(N=O)c(=O)[nH]c2ccc(Cl)c(Cl)c12

InChI Key: InChIKey=VAWWXAMUXVYWJP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052621   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50052621
PNG
(5,6-Dichloro-1H-quinoline-2,3,4-trione 3-oxime | C...)
Show SMILES Oc1c(N=O)c(=O)[nH]c2ccc(Cl)c(Cl)c12
Show InChI InChI=1S/C9H4Cl2N2O3/c10-3-1-2-4-5(6(3)11)8(14)7(13-16)9(15)12-4/h1-2H,(H2,12,14,15)
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Similars

Article
PubMed
n/an/a 170n/an/an/an/an/an/a



CoCensys Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes


J Med Chem 39: 3248-55 (1996)


Article DOI: 10.1021/jm960214k
BindingDB Entry DOI: 10.7270/Q2QC02KC
More data for this
Ligand-Target Pair