BDBM50053180 CHEMBL332565::Sodium; (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-((Z)-2-thiazol-5-yl-vinyl)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate
SMILES C[C@]1(\C=C/c2cncs2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
InChI Key InChIKey=MXGCFDVNRRWXED-QXBJNKKQSA-M
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50053180
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 2.86E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Compound was tested for inhibition of 503 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Compound was tested for inhibition of 604 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 4 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Escherichia coli.More data for this Ligand-Target Pair
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 2.86E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Compound was tested for inhibition of Bacillus licheniformis 749/C ,class A of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli AmpC ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Compound was tested for inhibition of Citrobacter freundii 1928, class C of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Compound was tested for inhibition of Pseudomonas aeruginosa 18SH ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1B(Escherichia coli (strain K12))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 1b from Escherichia coli.More data for this Ligand-Target Pair