BDBM50053180 CHEMBL332565::Sodium; (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-((Z)-2-thiazol-5-yl-vinyl)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate

SMILES C[C@]1(\C=C/c2cncs2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O

InChI Key InChIKey=MXGCFDVNRRWXED-QXBJNKKQSA-M

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50053180   

TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  2.86E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  2.20E+4nMAssay Description:Compound was tested for inhibition of 503 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  1.41E+4nMAssay Description:Compound was tested for inhibition of 604 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  1.43E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 4(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  1.40E+4nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 4 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  1.43E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  2.86E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus licheniformis)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  540nMAssay Description:Compound was tested for inhibition of Bacillus licheniformis 749/C ,class A of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  2.70E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli AmpC ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Citrobacter freundii)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  410nMAssay Description:Compound was tested for inhibition of Citrobacter freundii 1928, class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50:  8.90E+3nMAssay Description:Compound was tested for inhibition of Pseudomonas aeruginosa 18SH ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1B(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053180(CHEMBL332565 | Sodium; (2S,3S,5R)-3-methyl-4,4,7-t...)
Affinity DataIC50: >1.00E+7nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 1b from Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed