BDBM50053184 (2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::(2S,3S,5R)-3-(2-Cyano-vinyl)-3-methyl-4,4,7-trioxo-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::CHEMBL333078

SMILES C[C@]1(\C=C/C#N)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O

InChI Key InChIKey=JYGFUXUBGZBBAC-BJTZKDDDSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50053184   

TargetSugE(Salmonella newport)
Institute

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Salmonella enterica serotype Newport AM17274 cephalosporinase CMY-31 by UV spectrophotometer in presence of 100 uM of cephalothinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Klebsiella pneumoniae)
Institute

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Klebsiella pneumoniae HP205 cephalosporinase CMY-36 by UV spectrophotometer in presence of 100 uM of cephalothinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  2.10E+4nMAssay Description:Compound was tested for inhibition of Escherichia coli AmpC ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  7.50E+3nMAssay Description:Compound was tested for inhibition of Pseudomonas aeruginosa 18SH ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Institute

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of Escherichia coli beta-lactamase ACC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053184((2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-tr...)
Affinity DataIC50:  700nMAssay Description:Compound was tested for inhibition of Citrobacter freundii 1928, class C of Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed