BDBM50053545 7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-4-pyridin-3-yl-3H-naphtho[2,3-c]furan-1-one::CHEMBL340805

SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2cccnc2)c1

InChI Key InChIKey=ZGAZRCIVDSNGIC-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053545   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053545(7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-...)
Show SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2cccnc2)c1
Show InChI InChI=1S/C29H25NO5/c31-28-25-15-21-14-23(6-7-24(21)27(26(25)18-35-28)20-4-2-10-30-16-20)34-17-19-3-1-5-22(13-19)29(32)8-11-33-12-9-29/h1-7,10,13-16,32H,8-9,11-12,17-18H2
Affinity DataIC50: 720nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair