BDBM50053584 CHEMBL1977874
SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O
InChI Key InChIKey=HWODCHXORCTEGU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50053584
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:ATP competitive inhibition of human eEF-2K using 5 uM ATPMore data for this Ligand-Target Pair
3D Structure (crystal)TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...More data for this Ligand-Target Pair
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of eEF2K (unknown origin)More data for this Ligand-Target Pair
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of eEF2K (unknown origin)More data for this Ligand-Target Pair
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of eEF2K (unknown origin) using peptide MH-1 as substrate after 2 hrs by ADP-Glo luminescent assayMore data for this Ligand-Target Pair