BDBM50053589 (S)-3-Hydroxyphenylglycine::(S)-Amino-(3-hydroxy-phenyl)-acetic acid::3HPG::CHEMBL442347

SMILES N[C@H](C(O)=O)c1cccc(O)c1

InChI Key InChIKey=DQLYTFPAEVJTFM-ZETCQYMHSA-N

Data  12 KI  1 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50053589   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche Inc

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi:  8.40E+3nMMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(RAT)
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche Inc

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Novo Nordisk A/S

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50053589((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...)
Show SMILES N[C@H](C(O)=O)c1cccc(O)c1
Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
Affinity DataEC50:  6.80E+4nMAssay Description:Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair