BDBM50053823 CHEMBL130580::Isoquinoline-1-carboxylic acid [1-(1-ethylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-amide

SMILES CCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)c1nccc2ccccc12

InChI Key InChIKey=QXMOZKBLCRFIAZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053823   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053823(CHEMBL130580 | Isoquinoline-1-carboxylic acid [1-(...)
Affinity DataKi:  110nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053823(CHEMBL130580 | Isoquinoline-1-carboxylic acid [1-(...)
Affinity DataKi:  220nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50053823(CHEMBL130580 | Isoquinoline-1-carboxylic acid [1-(...)
Affinity DataKi:  350nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed