BDBM50054143 (+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::(+/-) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::(-) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::CHEMBL11265
SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
InChI Key InChIKey=XVCOCVUIJOUBOY-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50054143
Affinity DataIC50: 1.31E+4nMAssay Description:Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSBMore data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+4nMAssay Description:Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 10.6nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+4nMAssay Description:Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.More data for this Ligand-Target Pair
Affinity DataIC50: 2.33E+4nMAssay Description:Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatumMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of platelet glycoprotein alpha IIb beta3 integrin in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.72nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by displacement of [3H]8-OH-DPAT.More data for this Ligand-Target Pair
Affinity DataIC50: 6.61E+3nMAssay Description:Compound was evaluated for the binding affinity towards 5-hydroxytryptamine 1B receptor by displacement of [3H]ketanserin.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Compound was evaluated for the binding affinity towards Dopamine receptor D2 by displacement of [3H]SCH-23390.More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor by displacement of [3H]N-methyl-mesulergineMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor by displacement of [3H]5-HT.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSBMore data for this Ligand-Target Pair