BDBM50054213 3-(1-Carboxymethyl-1H-imidazol-4-yl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-propionic acid::CHEMBL136133
SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(Cc1cn(CC(O)=O)cn1)C(O)=O
InChI Key InChIKey=WIYBYBVRQRKSMW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50054213
Affinity DataIC50: 370nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair