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BDBM50055781 CHEMBL147652::[1-(3-Chloro-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid hydrazide

SMILES: COc1ccc2n(Cc3cccc(Cl)c3)c(C)c(CC(=O)NN)c2c1

InChI Key: InChIKey=JNDMWQNRNKLUDE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase A2, membrane associated


(Homo sapiens (Human))
BDBM50055781
PNG
(CHEMBL147652 | [1-(3-Chloro-benzyl)-5-methoxy-2-me...)
Show SMILES COc1ccc2n(Cc3cccc(Cl)c3)c(C)c(CC(=O)NN)c2c1
Show InChI InChI=1S/C19H20ClN3O2/c1-12-16(10-19(24)22-21)17-9-15(25-2)6-7-18(17)23(12)11-13-4-3-5-14(20)8-13/h3-9H,10-11,21H2,1-2H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.36E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of Human Nonpancreatic Secretory Phospholipase A2 through Chromogenic assay


J Med Chem 39: 5119-36 (1997)


Article DOI: 10.1021/jm960485v
BindingDB Entry DOI: 10.7270/Q2542MQ5
More data for this
Ligand-Target Pair