BDBM50056073 (2R,3R,4S)-2,4-Bis-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid::CHEMBL331577

SMILES CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc(OC)cc1

InChI Key InChIKey=BVNZXNOMGWQSDJ-JRFVFWCSSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056073   

TargetEndothelin receptor type B(Sus scrofa)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056073((2R,3R,4S)-2,4-Bis-(4-methoxy-phenyl)-1-[(methyl-p...)
Show SMILES CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H32N2O5/c1-5-14-26(2)22(28)16-27-15-21(17-6-10-19(31-3)11-7-17)23(25(29)30)24(27)18-8-12-20(32-4)13-9-18/h6-13,21,23-24H,5,14-16H2,1-4H3,(H,29,30)/t21-,23-,24+/m1/s1
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellar tissue using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056073((2R,3R,4S)-2,4-Bis-(4-methoxy-phenyl)-1-[(methyl-p...)
Show SMILES CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H32N2O5/c1-5-14-26(2)22(28)16-27-15-21(17-6-10-19(31-3)11-7-17)23(25(29)30)24(27)18-8-12-20(32-4)13-9-18/h6-13,21,23-24H,5,14-16H2,1-4H3,(H,29,30)/t21-,23-,24+/m1/s1
Affinity DataIC50: 176nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair