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BDBM50056442 (R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-methyl-amine::CHEMBL348285

SMILES: CN[C@@H]1Cc2cccc3ncn(C1)c23

InChI Key: InChIKey=BGMDLAIZBKXVQQ-SECBINFHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056442   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50056442
PNG
((R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-...)
Show SMILES CN[C@@H]1Cc2cccc3ncn(C1)c23
Show InChI InChI=1S/C11H13N3/c1-12-9-5-8-3-2-4-10-11(8)14(6-9)7-13-10/h2-4,7,9,12H,5-6H2,1H3/t9-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
355n/an/an/an/an/an/an/an/a



Pharmacia & Upjohn

Curated by ChEMBL


Assay Description
Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.


J Med Chem 40: 639-46 (1997)


Article DOI: 10.1021/jm960360q
BindingDB Entry DOI: 10.7270/Q29P30R9
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50056442
PNG
((R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-...)
Show SMILES CN[C@@H]1Cc2cccc3ncn(C1)c23
Show InChI InChI=1S/C11H13N3/c1-12-9-5-8-3-2-4-10-11(8)14(6-9)7-13-10/h2-4,7,9,12H,5-6H2,1H3/t9-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.46E+3n/an/an/an/an/an/an/an/a



Pharmacia & Upjohn

Curated by ChEMBL


Assay Description
Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.


J Med Chem 40: 639-46 (1997)


Article DOI: 10.1021/jm960360q
BindingDB Entry DOI: 10.7270/Q29P30R9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM50056442
PNG
((R)-5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl-...)
Show SMILES CN[C@@H]1Cc2cccc3ncn(C1)c23
Show InChI InChI=1S/C11H13N3/c1-12-9-5-8-3-2-4-10-11(8)14(6-9)7-13-10/h2-4,7,9,12H,5-6H2,1H3/t9-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>3.26E+3n/an/an/an/an/an/an/an/a



Pharmacia & Upjohn

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.


J Med Chem 40: 639-46 (1997)


Article DOI: 10.1021/jm960360q
BindingDB Entry DOI: 10.7270/Q29P30R9
More data for this
Ligand-Target Pair