BDBM50057090 (R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pentan-2-ylamino)-1-oxo-4-(4-propylphenyl)butan-2-ylamino)propanoic acid::(R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-(4-propyl-phenyl)-propylamino]-propionic acid::(R)-2-[(S)-1-(3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-(4-propyl-phenyl)-propylamino]-propionic acid::CHEMBL8474

SMILES CCCc1ccc(CC[C@H](N[C@H](C)C(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)Nc2ccccc2)cc1

InChI Key InChIKey=DFHTYEKEXQDADI-YNJKOYDBSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50057090   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  3.5nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  18nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  18nMAssay Description:Inhibition of matrix metalloproteinase-3(MMP-3).More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  18nMAssay Description:Inhibition of human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibitory activity against human collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057090((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article