BDBM50057915 2-(2-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole::CHEMBL43645
SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1ccccc1F)C(F)(F)F
InChI Key InChIKey=YWHWGDCPWAFBRB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50057915
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair