BDBM50058099 Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzo[1,3]dioxol-5-yl)-ethyl ester::CHEMBL296927

SMILES CC(=O)OCCc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl

InChI Key InChIKey=AOMQIATVHQSAEZ-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058099   

TargetEndothelin-1 receptor(Homo sapiens (Human))
ImmunoPharmaceutics Inc.

Curated by ChEMBL
LigandPNGBDBM50058099(Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5...)
Show SMILES CC(=O)OCCc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl
Show InChI InChI=1S/C20H18ClN3O8S2/c1-10-17(21)20(32-23-10)24-34(27,28)16-4-6-33-18(16)19(26)22-13-8-15-14(30-9-31-15)7-12(13)3-5-29-11(2)25/h4,6-8,24H,3,5,9H2,1-2H3,(H,22,26)
Affinity DataIC50: 4.5nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
ImmunoPharmaceutics Inc.

Curated by ChEMBL
LigandPNGBDBM50058099(Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5...)
Show SMILES CC(=O)OCCc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl
Show InChI InChI=1S/C20H18ClN3O8S2/c1-10-17(21)20(32-23-10)24-34(27,28)16-4-6-33-18(16)19(26)22-13-8-15-14(30-9-31-15)7-12(13)3-5-29-11(2)25/h4,6-8,24H,3,5,9H2,1-2H3,(H,22,26)
Affinity DataIC50: 2.57E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair