BDBM50058152 7-(2''-spiroindanyl)naltrexone::CHEMBL610293

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC1(Cc4ccccc4C1)C2=O)ccc3O

InChI Key InChIKey=WLGQGKOZUDOESI-NZHOUOPXSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50058152   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi:  0.25nMAssay Description:The compound tested for agonistic activity against Opioid receptor delta 1 using [3H]- NT1 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi:  1.5nMAssay Description:The compound tested for agonistic activity against Opioid receptor mu 1 using [3H]- DAMGO as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi: >3.00E+3nMAssay Description:The compound tested for agonistic activity against Opioid receptor kappa 1 as the [3H]- U-69,594 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50058152(7-(2''-spiroindanyl)naltrexone | CHEMBL610293)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed