BDBM50058449 4-(2-Ethyl-isothioureido)-benzoic acid ethyl ester; hydriodide::CHEMBL500901::CHEMBL545670

SMILES CCOC(=O)c1ccc(cc1)N=C(N)SCC

InChI Key InChIKey=DQZFMLXKFXWTBT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058449   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058449(4-(2-Ethyl-isothioureido)-benzoic acid ethyl ester...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50058449(4-(2-Ethyl-isothioureido)-benzoic acid ethyl ester...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase in brain (nNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50058449(4-(2-Ethyl-isothioureido)-benzoic acid ethyl ester...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against human vascular endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50058449(4-(2-Ethyl-isothioureido)-benzoic acid ethyl ester...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed