BDBM50059453 CHEMBL3393455

SMILES Fc1ccccc1C1c2c[nH]nc2NC2=C1C(=O)CNC2

InChI Key

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50059453   

TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059453(CHEMBL3393455)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059453(CHEMBL3393455)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p-38 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059453(CHEMBL3393455)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059453(CHEMBL3393455)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of TIE-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059453(CHEMBL3393455)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed